Glioblastoma is an aggressive brain cancer that remains extremely difficult to treat. Research into cancer cell evolution at JAX And it has the potential to reveal cell types that are rare or otherwise difficult to study but are important to cancer growth and survival. The technology also provides the opportunity to uncover molecules that control cell-to-cell communication between the many cell types that reside within a tumor, identifying potential drug targets. Single-cell sequencing can track how mutations spread through tumors and make some of them resistant to therapy. There are many possible applications, but it’s easy to see that focusing on one cell at a time provides a way to identify, characterize and better understand the effects of cellular differences within tumors. Provides a powerful new platform for investigating cancer. Areas of expertise include single cell transcriptomics, primate/human early embryonic development, maternal-fetal medicine, fetal programming, pluripotent cell biology, regulatory networks, tumor heterogeneity, circulating tumor cells. Single Cell Genomics CenterĪt JAX Genomic Medicine, led by Paul Robson, Ph.D. The recently established What is single cell genomics? Recent advances in the techniques for isolating single cells, together with methods for amplifying their genetic material, now make it possible to explore the genomes of single cells. Research into cancer cell variation at JAX That is increasing our understanding of each concept and, in some cases, is identifying new therapeutic targets. NCI-designated Jackson Laboratory Cancer Center The JAXCC comprises approximately 50 members with multidisciplinary expertise who are united in research aimed at understanding and targeting the genomic complexity of cancer.
Say goodbye to one-size-fits-all cancer treatments Driven by the desire to eradicate cancer, we are leading the future of cancer treatments by combining computational expertise with our unparalleled knowledge of mouse genetics.įor a better handle on where we are now, what challenges remain to be overcome, and what progress may be around the corner, here are a few key biological concepts, how they relate to cancer, and research at the The JAX Cancer Center The Jackson Laboratory Cancer Center (JAXCC) is a National Cancer Institute-designated Cancer Center complemented by institutional education, resource and service initiatives that support cancer research world-wide.
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